Association of Plasma Adiponectin and Oxidized Low-Density Lipoprotein with Carotid Intima-Media Thickness in Diabetic Nephropathy

摘要: Aims. We sought to determine the association between levels of adiponectin and oxidized low-density lipoprotein (ox-LDL) in patients with diabetic nephropathy as well their effect on carotid intima-media thickness (cIMT). Methods. Adiponectin ox-LDL were determined 25 without 94 at different stages including subjects hemodialysis. cIMT was measured using real-time B-mode ultrasonography. Results. Plasma increased significantly severity (P = 0.002), contrary which decreased disease < 0.001). higher late compared early 0.022). a significant negative predictor (β −5.45, P 0.023), independently confounding factors. There no correlation or either total sample population according staging. Cluster analysis showed that highest values, adiponectin, lowest included one cluster all assigned stage 5 nephropathy. Conclusions. and, therefore, other factors affecting this surrogate marker cardiovascular should be sought.