Continuous improvement in the immune system of HIV-infected children on prolonged antiretroviral therapy.
作者： Adriana Weinberg , Ruth Dickover , Paula Britto , Chengcheng Hu , Julie Patterson-Bartlett
DOI: 10.1097/QAD.0B013E3283189BB3
关键词: Viral disease 、 Immune system 、 Cellular immunity 、 Viral load 、 Virology 、 Immunopathology 、 CD4-CD8 Ratio 、 Biology 、 Immunology 、 Lentivirus 、 Acquired immunodeficiency syndrome (AIDS)
摘要: Background The goal of HAART is to promote reconstitution CD4+ T cells and other immune responses. We evaluated the extent kinetics in HIV-infected children over 144 weeks successful HAART.
elsevier.com
sci-hub.se 参考文章(48)
William T. Shearer, Howard M. Rosenblatt, Rebecca S. Gelman, Rebecca Oyomopito, Susan Plaeger, E.Richard Stiehm, Diane W. Wara, Steven D. Douglas, Katherine Luzuriaga, Elizabeth J. McFarland, Ram Yogev, Mobeen H. Rathore, Wende Levy, Bobbie L. Graham, Stephen A. Spector, Lymphocyte subsets in healthy children from birth through 18 years of age : The pediatric AIDS clinical trials group P1009 study The Journal of Allergy and Clinical Immunology. ,vol. 112, pp. 973- 980 ,(2003) , 10.1016/J.JACI.2003.07.003
Steven L Gortmaker, Michael Hughes, Joseph Cervia, Michael Brady, George M Johnson, George R Seage III, Lin Ye Song, Wayne M Dankner, James M Oleske, None, Effect of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1. The New England Journal of Medicine. ,vol. 345, pp. 1522- 1528 ,(2001) , 10.1056/NEJMOA011157
Mamoru Fujiwara, Masafumi Takiguchi, HIV-1-specific CTLs effectively suppress replication of HIV-1 in HIV-1-infected macrophages. Blood. ,vol. 109, pp. 4832- 4838 ,(2007) , 10.1182/BLOOD-2006-07-037481
Louis Alexander, Lisa Cuchura, B Joyce Simpson, Warren A. Andiman, Virologic and host characteristics of human immunodeficiency virus type 1-infected pediatric long term survivors. Pediatric Infectious Disease Journal. ,vol. 25, pp. 135- 141 ,(2006) , 10.1097/01.INF.0000199299.00345.83
Elizabeth Connick, Michael M. Lederman, Brian L. Kotzin, John Spritzler, Daniel R. Kuritzkes, Marty St. Clair, Anne D. Sevin, Lawrence Fox, Margo Heath Chiozzi, John M. Leonard, Franck Rousseau, Joana D'Arc Roe, Ana Martinez, Harold Kessler, Alan Landay, Immune Reconstitution in the First Year of Potent Antiretroviral Therapy and Its Relationship to Virologic Response The Journal of Infectious Diseases. ,vol. 181, pp. 358- 363 ,(2000) , 10.1086/315171
A. Weinberg, S. Pahwa, R. Oyomopito, V. J. Carey, B. Zimmer, L. Mofenson, A. Kovacs, S. K. Burchett, , Antimicrobial-specific cell-mediated immune reconstitution in children with advanced human immunodeficiency virus infection receiving highly active antiretroviral therapy. Clinical Infectious Diseases. ,vol. 39, pp. 107- 114 ,(2004) , 10.1086/420931
Andrew J. McMichael, Sarah L. Rowland-Jones, Cellular immune responses to HIV. Nature. ,vol. 410, pp. 980- 987 ,(2001) , 10.1038/35073658
R. E. McKinney, J. Rodman, C. Hu, P. Britto, M. Hughes, M. E. Smith, L. K. Serchuck, J. Kraimer, A. A. Ortiz, P. Flynn, R. Yogev, S. Spector, L. Draper, P. Tran, M. Scites, R. Dickover, A. Weinberg, C. Cunningham, E. Abrams, M. R. Blum, G. E. Chittick, L. Reynolds, M. Rathore, , Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021. Pediatrics. ,vol. 120, ,(2007) , 10.1542/PEDS.2006-0925
Urban Sester, Martina Sester, Hans Köhler, Hans W. Pees, Barbara C. Gärtner, Simon Wain-Hobson, Gennady Bocharov, Andreas Meyerhans, Maintenance of HIV-Specific Central and Effector Memory CD4 and CD8 T Cells Requires Antigen Persistence AIDS Research and Human Retroviruses. ,vol. 23, pp. 549- 553 ,(2007) , 10.1089/AID.2006.0234
Frank Maldarelli, Sarah Palmer, Martin S King, Ann Wiegand, Michael A Polis, JoAnn Mican, Joseph A Kovacs, Richard T Davey, Diane Rock-Kress, Robin Dewar, Shuying Liu, Julia A Metcalf, Catherine Rehm, Scott C Brun, George J Hanna, Dale J Kempf, John M Coffin, John W Mellors, ART Suppresses Plasma HIV-1 RNA to a Stable Set Point Predicted by Pretherapy Viremia PLOS Pathogens. ,vol. 3, ,(2007) , 10.1371/JOURNAL.PPAT.0030046