PREVENTION OF BROILER CHICK COCCIDIOSIS USING THE INACTIVATED SUBUNIT VACCINE COXABIC

作者: Tomasz Cencek , Irena Ziomko , Jacek Karamon , Aleksander Skoracki , Udi Ashash

DOI:

关键词: Animal scienceCoccidiosisInoculationEimeriaBroiler chickVaccinationBroilerVeterinary medicineCoccidiaBiologyDiclazuril

摘要: The efficacy of the vaccination breeding hens in prevention coccidiosis broiler chicks hatched from eggs laid by immunized with CoxAbic ® vaccine comparison to coming non-vaccinated was examined. Breeders were vaccinated 8 and 4 weeks before beginning egg laying. level Eimeria antibodies determined using ELISA: hen sera after chick at first day age. One hundred fifty six one-day-old divided into groups: group 1- groups 2, 3, - . Chicks 1, 2 3 maintained pens on concrete floor cages wire net floor. seeder each pen inoculated oral gavage 1 d age 50 oocysts coccidia species: E. maxima, acervulina, tenella. Broilers fed diet containing diclazuril At 34 broilers challenged sporulated (300 000 acervulina,150 60 tenella per bird). Six challenge intestinal lesion scores recorded. It demonstrated that used vaccinate breeders protected their progeny against caused coccidian species. estimated significantly higher than ones. characterized lowest score challenge.

参考文章(13)
N C Smith, M Wallach, C M Miller, R Morgenstern, R Braun, J Eckert, Maternal transmission of immunity to Eimeria maxima: enzyme-linked immunosorbent assay analysis of protective antibodies induced by infection. Infection and Immunity. ,vol. 62, pp. 1348- 1357 ,(1994) , 10.1128/IAI.62.4.1348-1357.1994
M Wallach, A Halabi, G Pillemer, O Sar-Shalom, D Mencher, M Gilad, U Bendheim, H D Danforth, P C Augustine, Maternal immunization with gametocyte antigens as a means of providing protective immunity against Eimeria maxima in chickens. Infection and Immunity. ,vol. 60, pp. 2036- 2039 ,(1992) , 10.1128/IAI.60.5.2036-2039.1992
Michael G. Wallach, David Mencher, Sinai Yarus, Graciella Pillemer, Amal Halabi, Thea Pugatsch, Eimeria maxima: Identification of gametocyte protein antigens Experimental Parasitology. ,vol. 68, pp. 49- 56 ,(1989) , 10.1016/0014-4894(89)90007-6
Joyce Johnson, W.Malcolm Reid, Anticoccidial drugs: Lesion scoring techniques in battery and floor-pen experiments with chickens Experimental Parasitology. ,vol. 28, pp. 30- 36 ,(1970) , 10.1016/0014-4894(70)90063-9
M. Wallach, N.C. Smith, R. Braun, J. Eckert, Potential control of chicken coccidiosis by maternal immunization Parasitology Today. ,vol. 11, pp. 262- 265 ,(1995) , 10.1016/0169-4758(95)80208-8
Michal Fried, David Mencher, Orit Sar-Shalom, Michael Wallach, Developmental gene expression of a 230-kilodalton macrogamete-specific protein of the avian coccidial parasite, Eimeria maxima Molecular and Biochemical Parasitology. ,vol. 51, pp. 251- 262 ,(1992) , 10.1016/0166-6851(92)90075-U
Michael Wallach, Nicholas C Smith, M Petracca, Catherine MD Miller, Johannes Eckert, Richard Braun, Eimeria maxima gametocyte antigens: potential use in a subunit maternal vaccine against coccidiosis in chickens Vaccine. ,vol. 13, pp. 347- 354 ,(1995) , 10.1016/0264-410X(95)98255-9
Michael Wallach, The importance of transmission-blocking immunity in the control of infections by apicomplexan parasites International Journal for Parasitology. ,vol. 27, pp. 1159- 1167 ,(1997) , 10.1016/S0020-7519(97)00113-6
D.J.P Ferguson, S.I Belli, N.C Smith, M.G Wallach, The development of the macrogamete and oocyst wall in Eimeria maxima: immuno-light and electron microscopy. International Journal for Parasitology. ,vol. 33, pp. 1329- 1340 ,(2003) , 10.1016/S0020-7519(03)00185-1