Bioorthogonal reactions challenged: DNA templated native chemical ligation during PCR

作者: Alexander Roloff , Oliver Seitz

DOI: 10.1039/C2SC20961F

关键词: Bioorthogonal chemistryCombinatorial chemistryNative chemical ligationTemplateCovalent bondBiochemistryPolymerase chain reactionA-DNADNAChemistry

摘要: … DNA directed synthesis offers fascinating opportunities for the programmable formation of functional molecules. For example, DNA templated chemistry has been used to facilitate drug …

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