Neural stem cells: ready for therapeutic applications?

作者: Simona Casarosa , Yuri Bozzi , Luciano Conti

DOI: 10.1186/2052-8426-2-31

关键词: Cell therapyMedicineBasic researchNeural stem cellAppropriate useBiological propertyTransplantationRegenerative medicineInduced pluripotent stem cellNeuroscience

摘要: Neural stem cells (NSCs) offer a unique and powerful tool for basic research regenerative medicine. However, the challenges that scientists face in comprehension of biology physiological function these are still many. Deciphering NSCs fundamental biological aspects represents indeed crucial step to control fate functional integration following transplantation, is essential safe appropriate use injury/disease conditions. In this review, we focus on properties discuss how may be exploited provide effective therapies neurological disorders. We also review ongoing NSC-based clinical trials diseases.

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