A pH-responsive activatable aptamer probe for targeted cancer imaging based on i-motif-driven conformation alteration

作者: Lv’an Yan , Hui Shi , Dinggeng He , Xiaoxiao He , Kemin Wang

DOI: 10.1007/S11426-016-5575-2

关键词: Cancer imagingCancer cellMolecular biologyAptamerHybridization probeFluorescenceChemistryDNABiophysicsAs1411 aptamerCytosine

摘要: We present here a pH-responsive activatable aptamer probe for targeted cancer imaging based on i-motif-driven conformation alteration. This pH-responsive activatable aptamer …

参考文章(28)
Anna Dembska, Bernard Juskowiak, Pyrene functionalized molecular beacon with pH-sensitive i-motif in a loop Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. ,vol. 150, pp. 928- 933 ,(2015) , 10.1016/J.SAA.2015.06.041
Andreas Becker, Carsten Hessenius, Kai Licha, Bernd Ebert, Uwe Sukowski, Wolfhard Semmler, Bertram Wiedenmann, Carsten Grötzinger, Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands. Nature Biotechnology. ,vol. 19, pp. 327- 331 ,(2001) , 10.1038/86707
Jin Huang, Le Ying, Xiaohai Yang, Yanjing Yang, Ke Quan, He Wang, Nuli Xie, Min Ou, Qifeng Zhou, Kemin Wang, Ratiometric fluorescent sensing of pH values in living cells by dual-fluorophore-labeled i-motif nanoprobes. Analytical Chemistry. ,vol. 87, pp. 8724- 8731 ,(2015) , 10.1021/ACS.ANALCHEM.5B01527
Yuanchen Dong, Zhongqiang Yang, Dongsheng Liu, DNA Nanotechnology Based on i-Motif Structures Accounts of Chemical Research. ,vol. 47, pp. 1853- 1860 ,(2014) , 10.1021/AR500073A
Colin D. Medley, Joshua E. Smith, Zhiwen Tang, Yanrong Wu, Suwussa Bamrungsap, Weihong Tan, Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells. Analytical Chemistry. ,vol. 80, pp. 1067- 1072 ,(2008) , 10.1021/AC702037Y
Linfeng Chen, Jiancheng Di, Changyan Cao, Yong Zhao, Ying Ma, Jia Luo, Yongqiang Wen, Weiguo Song, Yanlin Song, Lei Jiang, A pH-driven DNA nanoswitch for responsive controlled release Chemical Communications. ,vol. 47, pp. 2850- 2852 ,(2011) , 10.1039/C0CC04765A
Chunyan Wang, Zhenzhen Huang, Youhui Lin, Jinsong Ren, Xiaogang Qu, Artificial DNA nano-spring powered by protons. Advanced Materials. ,vol. 22, pp. 2792- 2798 ,(2010) , 10.1002/ADMA.201000445
Guangtao Song, Jinsong Ren, Recognition and regulation of unique nucleic acid structures by small molecules Chemical Communications. ,vol. 46, pp. 7283- 7294 ,(2010) , 10.1039/C0CC01312A
Weihong Tan, Michael J. Donovan, Jianhui Jiang, Aptamers from Cell-Based Selection for Bioanalytical Applications Chemical Reviews. ,vol. 113, pp. 2842- 2862 ,(2013) , 10.1021/CR300468W
Souvik Modi, Clément Nizak, Sunaina Surana, Saheli Halder, Yamuna Krishnan, Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell Nature Nanotechnology. ,vol. 8, pp. 459- 467 ,(2013) , 10.1038/NNANO.2013.92