RNAi: Gene Silencing Approach in C. elegans and H. sapiens
DOI: 10.9735/0976-0482.1.1.9-14
关键词: RNA-induced transcriptional silencing 、 Trans-acting siRNA 、 Cell biology 、 RNA-induced silencing complex 、 Argonaute 、 RNA interference 、 Non-coding RNA 、 Biology 、 Small interfering RNA 、 RNA silencing 、 Genetics
摘要: siRNAs (Short interfering RNAs) and miRNAs (microRNAs), which are mediate silencing via distinct mechanisms C. elegans Homo sapiens. The breaking of a double- stranded RNA (dsRNA) matching specific gene sequence into short pieces called RNA, trigger the degradation mRNA that matches its sequence. In this review, we discussed interference with principle application in recent biological research areas.
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