RNA interference as a potential therapeutic treatment for inflammation associated lung injury.
作者： Joanne Lomas-Neira , Alfred Ayala , Chun-Shiang Chung
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摘要: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remain important sources of morbidity for patients in the ICUs developed world. However, imagine having as a therapeutic tool, ability to regulate, tissue specific manner, expression given gene. RNA interference, potentially such method selectively suppressing protein expression, has evolved an tool study gene function targeted therapeutics. Significant progress been made identifying potential targets integral pathways leading development inflammation-associated injury. This review will discuss progress, thus far, application vivo interference-based therapy investigation
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