The efficacy of blueberry and grape seed extract combination on triple therapy for Helicobacter pylori eradication: a randomised controlled trial
作者： Chian-Sem Chua , Kuo-Ching Yang , Jui-Hao Chen , Yuh-Hwa Liu , Yi-Hsin Hsu
DOI: 10.3109/09637486.2016.1144716
关键词: Anti-ulcer Agent 、 Grape seed extract 、 Esomeprazole 、 Helicobacter pylori 、 Antibiotics 、 Gastritis 、 Proton-pump inhibitor 、 Medicine 、 Gastroenterology 、 Internal medicine 、 Clarithromycin 、 Traditional medicine
摘要: Helicobacter pylori is a major risk factor for gastritis, gastric ulcers and cancer. Traditional therapy with proton pump inhibitor antibiotics regarded as optimal H. eradication whereas, the rate unsatisfactory. Studies have reported that cranberry may inhibit adhesion to human mucus but lack of other berry extracts been evaluated in clinical study. Thus, 9-week add-on randomised controlled trial was conducted explore impact blueberry grape seed extract (BGE) combinations traditional eradication. In results, we found there no significant difference between group placebo intention-to-treat analysis per-protocol (94.64% versus 84.62%, p = 0.085). Diarrhoea, constipation epigastric pain were observed increasing during ingestion some cases. conclusion, this study indicated existed BGE under triple therapy.
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