Radiation dose calculations in persons receiving injection of samarium-153 EDTMP
作者： R.A. Holmes , K.W. Logan , W.A. Volkert
DOI:
关键词: Irradiation 、 Radiation therapy 、 Nuclear medicine 、 Bone tissue 、 Radionuclide 、 Chemistry 、 EDTMP 、 Urinary system 、 Radiation dose 、 Bone marrow
摘要: Samarium-153 EDTMP has been proposed as a radionuclide therapeutic agent to treat malignant bone tissue disorders. Data obtained from laboratory rats used calculate the radiation dose for humans following administration of (/sup 153/Sm)EDTMP. The data reveal that highest doses are present in skeleton and urinary bladder wall (bladder varies with frequency voiding). Skeletal activity was estimate marrow 153/Sm)EDTMP beta radiation. Although this indicates high irradiation it is only an approximation since inhomogeneously deposited surrounding produces variable distributions.
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