High dose radionuclide complexes for bone marrow treatment

作者: Kent R. Thoelke , Alan R. Fritzberg , Mark D. Hylarides , Lauren Marie Tatalick , Paul G. Abrams

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摘要: The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near such as cancer, myeloproliferative diseases, autoimmune infectious metabolic diseases genetic with compositions having their active ingredient radionuclide complexed chelating agent macrocyclic aminophosphonic acid.

参考文章(162)
Frederick Appelbaum, Janet F. Eary, Michael Stabin, Shelley Hartnett, Carolyn Collins, Cheryl Vernon, Steve Petersdorf, Stanley J. Addison, Edwin E. Gordon, Melissa Baker, Sandra Ferency, Samarium-153-EDTMP Biodistribution and Dosimetry Estimation The Journal of Nuclear Medicine. ,vol. 34, pp. 1031- 1036 ,(1993)
Wilson D, Mc Crary A, Substituted alkanolamine chelating agents ,(1970)
Masakazu c, Noriko c, o Toyo Boseki K.K. Monden, o Toyo Boseki K.K. Yokota, o Toyo Boseki K.K. Tanaka, Masahiro c, Susumu c, Hideyuki c, Shigeji c, o Toyo Boseki K.K. Konagaya, o Toyo Boseki K.K. Seko, o Toyo Boseki K.K. Arimori, Organic solvent-soluble mucopolysaccharide, antibacterial antithrombogenic composition and medical material ,(1996)
Michael G. Stabin, Keith F. Eckerman, Lawrence E. Williams, Jeffrey C. Ryman, Bremsstrahlung radiation dose in Yttrium-90 therapy applications The Journal of Nuclear Medicine. ,vol. 35, pp. 1377- 1380 ,(1994)
Janet F. Eary, Joseph G. Rajendran, William Bensinger, Larry D. Durack, Cheryl Vernon, Alan Fritzberg, High-dose 166Ho-DOTMP in myeloablative treatment of multiple myeloma: pharmacokinetics, biodistribution, and absorbed dose estimation. The Journal of Nuclear Medicine. ,vol. 43, pp. 1383- 1390 ,(2002)
Linda M. Gustavson, John M. Reno, Louis J. Theodore, Two-step pretargeting methods using improved bidtin-active agent conjugates ,(1997)
David A. Wilson, Wynn A. Volkert, Jaime Simon, Bone seeking Tc-99m complexes of phosphonate derivatives of polyamidoamines ,(1984)
Melinda Guzman-Harty, Joseph Schaller, Milo Duane Hilty, Steven N. Anderson, Theresa Siu-Ling Wai Lee, Lisa Ann Reaves, Jin-Zhou Liu, Terry Bruce Mazer, Water-Miscible esters of mono- and diglycerides having antimicrobial activity and their use in inhibiting infection ,(1996)
R.A. Holmes, K.W. Logan, W.A. Volkert, Radiation dose calculations in persons receiving injection of samarium-153 EDTMP The Journal of Nuclear Medicine. ,vol. 28, pp. 505- 509 ,(1987)