Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

作者: David Ng , Graham M Pitcher , Rachel K Szilard , Andréa Sertié , Marijana Kanisek

DOI: 10.1371/JOURNAL.PBIO.1000041

关键词: Synaptic plasticityBiologyPostsynaptic densityLTP inductionLong-term potentiationBiochemistryNMDA receptorNonsynaptic plasticityExcitatory postsynaptic potentialNeuroscienceMetaplasticity

摘要: The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Here we …

参考文章(74)
Holger Husi, Malcolm A. Ward, Jyoti S. Choudhary, Walter P. Blackstock, Seth G. N. Grant, Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nature Neuroscience. ,vol. 3, pp. 661- 669 ,(2000) , 10.1038/76615
Peer Bork, Georg Beckmann, The CUB domain. A widespread module in developmentally regulated proteins. Journal of Molecular Biology. ,vol. 231, pp. 539- 545 ,(1993) , 10.1006/JMBI.1993.1305
Robert H. Scannevin, Richard L. Huganir, Postsynaptic organisation and regulation of excitatory synapses Nature Reviews Neuroscience. ,vol. 1, pp. 133- 141 ,(2000) , 10.1038/35039075
Seth G. N. Grant, Walter P. Blackstock, Proteomics in Neuroscience: From Protein to Network The Journal of Neuroscience. ,vol. 21, pp. 8315- 8318 ,(2001) , 10.1523/JNEUROSCI.21-21-08315.2001
DJ Laurie, PH Seeburg, Regional and developmental heterogeneity in splicing of the rat brain NMDAR1 mRNA The Journal of Neuroscience. ,vol. 14, pp. 3180- 3194 ,(1994) , 10.1523/JNEUROSCI.14-05-03180.1994
Ya-Ping Tang, Eiji Shimizu, Gilles R Dube, Claire Rampon, Geoffrey A Kerchner, Min Zhuo, Guosong Liu, Joe Z Tsien, None, Genetic enhancement of learning and memory in mice Nature. ,vol. 401, pp. 63- 69 ,(1999) , 10.1038/43432
D. M. Bannerman, B. Niewoehner, L. Lyon, C. Romberg, W. B. Schmitt, A. Taylor, D. J. Sanderson, J. Cottam, R. Sprengel, P. H. Seeburg, G. Kohr, J. N. P. Rawlins, NMDA receptor subunit NR2A is required for rapidly acquired spatial working memory but not incremental spatial reference memory. The Journal of Neuroscience. ,vol. 28, pp. 3623- 3630 ,(2008) , 10.1523/JNEUROSCI.3639-07.2008
David P. Wolfer, Rime Madani, Paolo Valenti, Hans-Peter Lipp, Extended analysis of path data from mutant mice using the public domain software Wintrack. Physiology & Behavior. ,vol. 73, pp. 745- 753 ,(2001) , 10.1016/S0031-9384(01)00531-5
Rolf Sprengel, Bettina Suchanek, Carla Amico, Rossella Brusa, Nail Burnashev, Andrei Rozov, Øivind Hvalby, Vidar Jensen, Ole Paulsen, Per Andersen, Jeansok J Kim, Richard F Thompson, William Sun, Lorna C Webster, Seth G.N Grant, Jens Eilers, Arthur Konnerth, Jianying Li, James O McNamara, Peter H Seeburg, Importance of the Intracellular Domain of NR2 Subunits for NMDA Receptor Function In Vivo Cell. ,vol. 92, pp. 279- 289 ,(1998) , 10.1016/S0092-8674(00)80921-6
C. Geoffrey Lau, R. Suzanne Zukin, NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders Nature Reviews Neuroscience. ,vol. 8, pp. 413- 426 ,(2007) , 10.1038/NRN2153