Dendritic Spines: The Locus of Structural and Functional Plasticity
作者： Carlo Sala , Menahem Segal
DOI: 10.1152/PHYSREV.00012.2013
关键词: Structural plasticity 、 Locus (genetics) 、 Neuroscience 、 Dendritic spine 、 Biology 、 Synapse formation 、 Structure and function 、 Neuroplasticity
摘要: The introduction of high-resolution time lapse imaging and molecular biological tools has changed dramatically the rate progress towards understanding complex structure-function relations in synapses central spiny neurons. Standing issues, including sequence structural processes leading to formation, morphological change, longevity dendritic spines, as well functions spines neurological/psychiatric diseases are being addressed a growing number recent studies. There still unsettled issues with respect spine formation plasticity: Are formed first, followed by synapse or emergence spine? What immediate long-lasting changes properties following exposure plasticity-producing stimulation? Is volume/shape indicative its function? These other this review, which highlights complexity pathways involved regulation structure function, contributes synaptic interactions health disease.
sci-hub.se 参考文章(593)
Jubin Ryu, Lidong Liu, Tak Pan Wong, Dong Chuan Wu, Alain Burette, Richard Weinberg, Yu Tian Wang, Morgan Sheng, A critical role for myosin IIb in dendritic spine morphology and synaptic function Neuron. ,vol. 49, pp. 175- 182 ,(2006) , 10.1016/J.NEURON.2005.12.017
E Gould, CS Woolley, M Frankfurt, BS McEwen, Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood The Journal of Neuroscience. ,vol. 10, pp. 1286- 1291 ,(1990) , 10.1523/JNEUROSCI.10-04-01286.1990
Andrew J. Giessel, Bernardo L. Sabatini, M1 Muscarinic Receptors Boost Synaptic Potentials and Calcium Influx in Dendritic Spines by Inhibiting Postsynaptic SK Channels Neuron. ,vol. 68, pp. 936- 947 ,(2010) , 10.1016/J.NEURON.2010.09.004
Ben Chih, Shehla Khan Afridi, Lorraine Clark, Peter Scheiffele, Disorder-associated mutations lead to functional inactivation of neuroligins Human Molecular Genetics. ,vol. 13, pp. 1471- 1477 ,(2004) , 10.1093/HMG/DDH158
Yury Kovalchuk, Jens Eilers, John Lisman, Arthur Konnerth, NMDA Receptor-Mediated Subthreshold Ca2+ Signals in Spines of Hippocampal Neurons The Journal of Neuroscience. ,vol. 20, pp. 1791- 1799 ,(2000) , 10.1523/JNEUROSCI.20-05-01791.2000
Marta Zagrebelsky, Andreas Holz, Georg Dechant, Yves-Alain Barde, Tobias Bonhoeffer, Martin Korte, The p75 Neurotrophin Receptor Negatively Modulates Dendrite Complexity and Spine Density in Hippocampal Neurons The Journal of Neuroscience. ,vol. 25, pp. 9989- 9999 ,(2005) , 10.1523/JNEUROSCI.2492-05.2005
Angel Matias Sanchez, Marina Ines Flamini, Chiara Baldacci, Lorenzo Goglia, Andrea Riccardo Genazzani, Tommaso Simoncini, Estrogen Receptor-α Promotes Breast Cancer Cell Motility and Invasion via Focal Adhesion Kinase and N-WASP Molecular Endocrinology. ,vol. 24, pp. 2114- 2125 ,(2010) , 10.1210/ME.2010-0252
V. Endris, B. Wogatzky, U. Leimer, D. Bartsch, M. Zatyka, F. Latif, E. R. Maher, G. Tariverdian, S. Kirsch, D. Karch, G. A. Rappold, The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 11754- 11759 ,(2002) , 10.1073/PNAS.162241099
Andrew M. Hamilton, Won Chan Oh, Hugo Vega-Ramirez, Ivar S. Stein, Johannes W. Hell, Gentry N. Patrick, Karen Zito, Activity-Dependent Growth of New Dendritic Spines Is Regulated by the Proteasome Neuron. ,vol. 74, pp. 1023- 1030 ,(2012) , 10.1016/J.NEURON.2012.04.031
Wendou Yu, Jai Polepalli, Dhananjay Wagh, Jayakumar Rajadas, Robert Malenka, Bingwei Lu, A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines. Human Molecular Genetics. ,vol. 21, pp. 1384- 1390 ,(2012) , 10.1093/HMG/DDR576