Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy".

作者: Elysia A. Masters , Ryan P. Trombetta , Karen L. de Mesy Bentley , Brendan F Boyce , Ann Lindley Gill

DOI: 10.1038/S41413-019-0061-Z

关键词: MedicineDiseaseAbscessBone cellImmunologyAntibioticsBone marrowStaphylococcus aureusBone InfectionOsteomyelitis

摘要: … aureus intracellular persistence in bone cells has not been substantiated in vivo, which … such as antimicrobial implant coatings and antibiotic impregnated 3D-printed scaffolds represent …

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