Combinations of a hcv inhibitor such as bicyclic pyrrole derivatives and a therapeutic agent

作者: Zhengxian Gu , Frederick C. Lahser

DOI:

关键词: Pyrrole derivativesHcv proteaseHepatitis C virusBicyclic moleculePharmacologyVirologyCombination ProductChemistry

摘要: The present invention is directed to a combination product for treating or ameliorating hepatitis C virus (HCV) infection disorders symptoms associated therewith in subject need thereof comprising, HCV inhibitor and one more therapeutic agents selected from either both protease different administered an effective amount the subject.

参考文章(21)
Juliette Holland, Ivan Bastian, Rodney M. Ratcliff, Mary Y. Beers, Patricia Hahesy, Hugh Harley, David R. Shawl, Geoffrey D. Higgins, Hepatitis C genotyping by direct sequencing of the product from the Roche AMPLICOR test: methodology and application to a South Australian population. Pathology. ,vol. 30, pp. 192- 195 ,(1998) , 10.1080/00313029800169226
Hitoshi Hochigai, Hidenori Kimura, Hiroyuki Nakahira, Bicyclic pyrrole derivatives ,(2005)
Gary Mitchell Karp, James Jan Takasugi, Anthony Allan Turpoff, Richard Gerald Wilde, Guangming Chen, Peter Seongwoo Hwang, Hongyu Ren, Alexander Arefolov, Jeffrey Allen Campbell, Methods for treating hepatitis c ,(2005)
Alice K. Wheeler, Gregory W. Lambert, Charles A. Rosenblatt, System and method for point of sale cash rebates ,(2005)
Amin Nomeir, Gary Mitchell Karp, Steven D. Paget, Guangming Chen, Hongyu Ren, F. George Njoroge, Chunshi Li, William Joseph Lennox, Xiaoyan Zhang, Nanjing Zhang, Malcolm Maccoss, Christie Morrill, Compounds and methods for antiviral treatment ,(2010)
Stanley R. Krystek, Ligaya M. Simpkins, Lawrence G. Hamann, Akbar Nayeem, Zheming Ruan, James J. Li, Haixia Wang, Shung C. Wu, Christopher B. Cooper, Inhibitors of 11-beta hydroxysteroid dehydrogenase type i ,(2006)