Compounds and methods for antiviral treatment

作者: Amin Nomeir , Gary Mitchell Karp , Steven D. Paget , Guangming Chen , Hongyu Ren

DOI:

关键词:

摘要: The present invention is directed to compounds of formula (I) and forms pharmaceutical compositions thereof useful for treating a viral infection, or affecting activity by modulating replication.

参考文章(25)
Patrice Selles, Mafalda Nina, Fredrik Cederbaum, Florence Marie-Emilie Bonnaterre, William Guy Whittingham, Jane Elizabeth Wibley, 4-aza indole derivatives and their use as fungicides ,(2008)
Laurie L. Hill, The Orange Book Nature Reviews Drug Discovery. ,vol. 4, pp. 621- 621 ,(2005) , 10.1038/NRD1804
Kung-Cheng Chen, Lung-Chuan Huang, Built-up container ,(2005)
Camille G. Wermuth, The practice of medicinal chemistry Academic Press/Elsevier. ,(2015)
Finton Sirockin, Nils Ostermann, Jonathan Mark Sutton, Christopher Antony Hurley, Amanda Fillmore, Christopher Higgs, Neil Victor Harris, David Edward Clark, Robert Edward Mackenzie, Garry Fenton, Stephen John Dunsdon, Daniel Kaspar Baeschlin, Sussie Lerche Krintel, Condensed heterocyclic compounds useful as dpp-iv inhibitors ,(2006)
Lianhong Xu, Iestyn R. Lewis, Steven K. Davidsen, James B. Summers, Transition metal catalyzed synthesis of 5-azaindoles Tetrahedron Letters. ,vol. 39, pp. 5159- 5162 ,(1998) , 10.1016/S0040-4039(98)00986-1
Keril J Blight, Alexander A Kolykhalov, Charles M Rice, Efficient Initiation of HCV RNA Replication in Cell Culture Science. ,vol. 290, pp. 1972- 1974 ,(2000) , 10.1126/SCIENCE.290.5498.1972
Thomas Pietschmann, Volker Lohmann, Artur Kaul, Nicole Krieger, Gabriele Rinck, Gabriel Rutter, Dennis Strand, Ralf Bartenschlager, Persistent and Transient Replication of Full-Length Hepatitis C Virus Genomes in Cell Culture Journal of Virology. ,vol. 76, pp. 4008- 4021 ,(2002) , 10.1128/JVI.76.8.4008-4021.2002