Karyotyping means and method

作者: Nicole Hussey , Colin Matthews

DOI:

关键词: Chromosomal dnaBiologyDNAKaryotypeChromosomeGeneticsLabelling

摘要: A method of comparing at least one chromosome or part thereof from a cell an individual with unknown kyryotype the corresponding known karyotype. The includes steps of: (a) obtaining DNA derived single karyotype; (b) amplifying chromosomal karyotype sufficiently for comparative purposes: (c) labelling amplifed first label and second label, being detectably different; (d) hybridising labelled spread, amplified spread; (e) forming image relative amount as function position on thereof. It is also possible in to add extra primers highlight specific loci interest. may be used preimplantation diagnosis (PGD) source.

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