作者: Nicole Hussey , Colin Matthews
DOI:
关键词: Chromosomal dna 、 Biology 、 DNA 、 Karyotype 、 Chromosome 、 Genetics 、 Labelling
摘要: A method of comparing at least one chromosome or part thereof from a cell an individual with unknown kyryotype the corresponding known karyotype. The includes steps of: (a) obtaining DNA derived single karyotype; (b) amplifying chromosomal karyotype sufficiently for comparative purposes: (c) labelling amplifed first label and second label, being detectably different; (d) hybridising labelled spread, amplified spread; (e) forming image relative amount as function position on thereof. It is also possible in to add extra primers highlight specific loci interest. may be used preimplantation diagnosis (PGD) source.