Amplifying information from genetic material containing many fragments, useful e.g. for analyzing frequency of chromosomes in oocytes

作者: Wolfgang Mann , Elke Holinski-Feder

DOI:

关键词: Molecular biologyBinding siteBiologyBioinformatics

摘要: Amplifying genetic information from material (B) that contains many fragments (B') of material, separated each other, comprising using PCR with primers (P) are complementary to binding sites present at locations in (B), is new. by loctions (B). Each site adjacent one the target sequence, predetermined length, so amplification product (AP) essentially only amplified sequences comprise a specific target, suitable for detection hybridization.