Non-proteolytic method for the determination of analytes in keratinized structures

摘要: Methods that permit the rapid release of one or more analytes from head body hair other keratinized structures an individual (who may previously have ingested analytes) are provided. The methods can include contacting structure with a reducing agent but not proteolytic agent. further identification and quantification by known analytical techniques such as immunoassays. described do damage analyte cause harmful effects on subsequently-used detection probe (e.g., antibody).