Morphometric studies of the entorhinal cortex in neuropsychiatric patients and controls: clusters of heterotopically displaced lamina II neurons are not indicative of schizophrenia

摘要: Subtle cytoarchitectural abnormalities of the rostral entorhinal cortex have been reported to be characteristic for schizophrenics. A main finding was heterotopic displacement clusters lamina II neurons (which appeared morphologically immature) into layer III. Recent findings suggesting a considerable heterogeneity normal renewed interest in this problem and prompted question extent which `aberrantly' located cell are really disease-related. Being blind clinical diagnosis, we analyzed quantitatively amount heterotopias schizophrenics (n=31), controls (n=45) depressive patients (n=7). It revealed that occurred with roughly same frequency (amount per section). In depressives, there were significantly more than (right hemisphere). Our data show common part human not suitable neuroanatomical marker schizophrenia.