作者: Peter Falkai , Eleni Parlapani , Oliver Gruber , Andrea Schmitt
DOI: 10.1007/978-1-4419-0913-8_7
关键词: Brain development 、 Conceptual thinking 、 Schizophrenia 、 Neuropathology 、 Neuroscience 、 Adverse conditions 、 Hippocampus 、 Fractional anisotropy 、 Medicine 、 Pathogenesis
摘要: A change in conceptual thinking about the pathogenesis of schizophrenia has occurred over past decades. It is now hypothesized that disorder its origin on brain developmental neuropathology. The so-called neurodevelopmental hypothesis proposes related to adverse conditions leading abnormal development during pre- or postnatal period. This consequently leads long-term changes structure and malfunction, predisposing term functional deficits symptoms respond antidopaminergic drugs (Weinberger 1996).