DMD-based software-configurable spatially-offset Raman spectroscopy for spectral depth-profiling of optically turbid samples
作者： Zhiyu Liao , Faris Sinjab , Graham Gibson , Miles Padgett , Ioan Notingher
DOI: 10.1364/OE.24.012701
关键词: Optoelectronics 、 Optics 、 Spatially offset Raman spectroscopy 、 Raman scattering 、 Software 、 Attenuated total reflection 、 Optical path 、 Materials science 、 Infrared spectroscopy 、 Raman spectroscopy 、 Offset (computer science)
摘要: Spectral depth-profiling of optically turbid samples is high interest to a broad range applications. We present method for measuring spatially-offset Raman spectroscopy (SORS) over length scales by incorporating digital micro-mirror device (DMD) into sample-conjugate plane in the detection optical path. The DMD can be arbitrarily programmed collect/reject light at spatial positions 2D plane, allowing spatially offset measurements. demonstrate several geometries, including annular and simultaneous multi-offset modalities, both macro- micro-SORS measurements, all on same instrument. Compared other SORS DMD-based provides more flexibility with only minimal additional experimental complexity subsurface collection.
osapublishing.org参考文章(28)
Claudia Conti, Chiara Colombo, Marco Realini, Pavel Matousek, Subsurface analysis of painted sculptures and plasters using micrometre‐scale spatially offset Raman spectroscopy (micro‐SORS) Journal of Raman Spectroscopy. ,vol. 46, pp. 476- 482 ,(2015) , 10.1002/JRS.4673
Pavel Matousek, Nicholas Stone, None, Development of deep subsurface Raman spectroscopy for medical diagnosis and disease monitoring Chemical Society Reviews. ,vol. 45, pp. 1794- 1802 ,(2016) , 10.1039/C5CS00466G
C. Conti, M. Realini, C. Colombo, P. Matousek, Comparison of key modalities of micro-scale spatially offset Raman spectroscopy Analyst. ,vol. 140, pp. 8127- 8133 ,(2015) , 10.1039/C5AN01900A
Neil J. Everall, Confocal Raman Microscopy: Why the Depth Resolution and Spatial Accuracy Can Be Much Worse Than You Think Applied Spectroscopy. ,vol. 54, pp. 1515- 1520 ,(2000) , 10.1366/0003702001948439
Pavel Matousek, Inverse Spatially Offset Raman Spectroscopy for Deep Noninvasive Probing of Turbid Media Applied Spectroscopy. ,vol. 60, pp. 1341- 1347 ,(2006) , 10.1366/000370206778999102
Matthew Bloomfield, Darren Andrews, Paul Loeffen, Craig Tombling, Tim York, Pavel Matousek, Non-invasive identification of incoming raw pharmaceutical materials using Spatially Offset Raman Spectroscopy Journal of Pharmaceutical and Biomedical Analysis. ,vol. 76, pp. 65- 69 ,(2013) , 10.1016/J.JPBA.2012.11.046
Ioan Notingher, Robert E. Imhof, Peng Xiao, Flavius C. Pascut, Spectral Depth Profiling of Arbitrary Surfaces by Thermal Emission Decay—Fourier Transform Infrared Spectroscopy Applied Spectroscopy. ,vol. 57, pp. 1494- 1501 ,(2003) , 10.1366/000370203322640134
Jennifer-Lynn H. Demers, Francis W.L. Esmonde-White, Karen A. Esmonde-White, Michael D. Morris, Brian W. Pogue, Next-generation Raman tomography instrument for non-invasive in vivo bone imaging Biomedical Optics Express. ,vol. 6, pp. 793- 806 ,(2015) , 10.1364/BOE.6.000793
Ioan Notingher, Robert E. Imhof, Mid-infrared in vivo depth-profiling of topical chemicals on skin Skin Research and Technology. ,vol. 10, pp. 113- 121 ,(2004) , 10.1111/J.1600-0846.2004.61.X
P. Matousek, I. P. Clark, E. R. C. Draper, M. D. Morris, A. E. Goodship, N. Everall, M. Towrie, W. F. Finney, A. W. Parker, Subsurface Probing in Diffusely Scattering Media Using Spatially Offset Raman Spectroscopy Applied Spectroscopy. ,vol. 59, pp. 393- 400 ,(2005) , 10.1366/0003702053641450