Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
作者： Cathy Tournier , Patricia Hess , Derek D Yang , Jie Xu , Tod K Turner
DOI: 10.1126/SCIENCE.288.5467.870
关键词: APAF1 、 Caspase 3 、 Cytochrome c 、 Molecular biology 、 Cell biology 、 Apoptosis 、 Signal transduction 、 Biology 、 Caspase-9 、 Mitochondrion 、 Caspase 、 Multidisciplinary
摘要: The c-Jun NH2-terminal kinase (JNK) is activated when cells are exposed to ultraviolet (UV) radiation. However, the functional consequence of JNK activation in UV-irradiated cells has …
sciencemag.org
core.ac.uk
harvard.edu
elsevier.com
researchgate.net 参考文章(20)
Asim Khwaja, Akt is more than just a Bad kinase Nature. ,vol. 401, pp. 33- 34 ,(1999) , 10.1038/43354
Axel Behrens, Maria Sibilia, Erwin F Wagner, None, Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation Nature Genetics. ,vol. 21, pp. 326- 329 ,(1999) , 10.1038/6854
Junying Yuan, Bruce A. Yankner, Caspase activity sows the seeds of neuronal death. Nature Cell Biology. ,vol. 1, ,(1999) , 10.1038/10037
Kazuhito Yamamoto, Hidenori Ichijo, Stanley J. Korsmeyer, BCL-2 Is Phosphorylated and Inactivated by an ASK1/Jun N-Terminal Protein Kinase Pathway Normally Activated at G2/M Molecular and Cellular Biology. ,vol. 19, pp. 8469- 8478 ,(1999) , 10.1128/MCB.19.12.8469
Y Tony Ip, Roger J Davis, Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development. Current Opinion in Cell Biology. ,vol. 10, pp. 205- 219 ,(1998) , 10.1016/S0955-0674(98)80143-9
R S Johnson, B van Lingen, V E Papaioannou, B M Spiegelman, A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes & Development. ,vol. 7, pp. 1309- 1317 ,(1993) , 10.1101/GAD.7.7B.1309
S. Haldar, N. Jena, C. M. Croce, Inactivation of Bcl-2 by phosphorylation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 4507- 4511 ,(1995) , 10.1073/PNAS.92.10.4507
Gerard Evan, Trevor Littlewood, A Matter of Life and Cell Death Science. ,vol. 281, pp. 1317- 1322 ,(1998) , 10.1126/SCIENCE.281.5381.1317
Anne Roulston, Christoph Reinhard, Payman Amiri, Lewis T. Williams, Early Activation of c-Jun N-terminal Kinase and p38 Kinase Regulate Cell Survival in Response to Tumor Necrosis Factor α Journal of Biological Chemistry. ,vol. 273, pp. 10232- 10239 ,(1998) , 10.1074/JBC.273.17.10232
Julian Downward, Mechanisms and consequences of activation of protein kinase B/Akt. Current Opinion in Cell Biology. ,vol. 10, pp. 262- 267 ,(1998) , 10.1016/S0955-0674(98)80149-X