The Use of Monoclonal Antibodies for Studying the Fibrin Polymerization
作者： E. V. Lugovskoi
关键词: Factor XIII 、 Chemistry 、 Thrombin 、 Monoclonal antibody 、 Epitope 、 Biochemistry 、 Enzyme 、 Polymerization 、 Fibrin 、 Fibrinogen 、 Molecular biology
摘要: Examples of using monoclonal antibodies (MAb) for studying the fibrin polymerization mechanism are considered. MAb with epitopes situated in sites or recognition enzymes thrombin, plasminogen, and factor XIII, which functional partners fibrin, primarily discussed. The to various regions Aα, Bβ, γ polypeptide chains functionally important E, D, αC domains successively described.
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