Cardiovascular complications in patients with primary aldosteronism

摘要: Primary aldosteronism (PA) is widely believed to be a relatively benign form of hypertension associated with low incidence vascular complications. However, several recent studies showed that cardiovascular complications were not rare in PA. PA known as one the most typical forms sodium-sensitive hypertension. Recently, we found sodium sensitivity blood pressure was marker for greater risk complications, especially stroke, patients essential Therefore, investigated 58 confirmed Conn's adenoma. Cardiovascular 34% patients. Coronary artery disease only patient (1.7%), angina pectoris. Stroke nine (15.5%), four (6.9%) cerebral infarctions and five (8.6%) hemorrhages. Proteinuria renal insufficiency 14 (24.1%) 4 patients, respectively. The infarction men than women. prevalence proteinuria without stroke (P = 0.03) among those aged older 40 years. These results indicated proteinuria, common PA, might an indicator target-organ damage.