Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer

作者: Tetsuya Mitsudomi , Yasushi Yatabe

DOI: 10.1111/J.1742-4658.2009.07448.X

关键词: ROR1GefitinibGRB7Cancer researchReceptor tyrosine kinaseBiologyERBB3Tyrosine kinaseEpidermal growth factor receptorJAK-STAT signaling pathway

摘要: … G598V mutations were found in domain IV. These EGFR mutations occur independently of EGFR vIII and provide an alternative mechanism for EGFR activation in glioblastomas [[8]]. …

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