EGFR mutation is specific for terminal respiratory unit type adenocarcinoma.

作者: Yasushi Yatabe , Takayuki Kosaka , Takashi Takahashi , Tetsuya Mitsudomi

DOI: 10.1097/01.PAS.0000157935.28066.35

关键词: MedicineHyperplasiaAtypical adenomatous hyperplasiaLung cancerGefitinibPathologyAdenocarcinomaCarcinogenesisEpidermal growth factor receptorCancer

摘要: … Recently, two groups published novel mutations of the EGFR, … significance of the mutations with special reference to the TRU-… , a part of which we previously reported on EGFR mutation. …

参考文章(49)
G. Singh, C. Torikata, S. L. Katyal, Carcinoma of type II pneumocytes: immunodiagnosis of a subtype of "bronchioloalveolar carcinomas". American Journal of Pathology. ,vol. 102, pp. 195- 208 ,(1981)
Shuta Tomida, Katsumi Koshikawa, Yasushi Yatabe, Tomoko Harano, Nobuhiko Ogura, Tetsuya Mitsudomi, Masato Some, Kiyoshi Yanagisawa, Toshitada Takahashi, Hirotaka Osada, Takashi Takahashi, Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients Oncogene. ,vol. 23, pp. 5360- 5370 ,(2004) , 10.1038/SJ.ONC.1207697
Steven A. Ahrendt, P. Anthony Decker, Enas A. Alawi, Yong-ran Zhu, Montserrat Sanchez-Cespedes, Stephen C. Yang, George B. Haasler, André Kajdacsy-Balla, Michael J. Demeure, David Sidransky, Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung. Cancer. ,vol. 92, pp. 1525- 1530 ,(2001) , 10.1002/1097-0142(20010915)92:6<1525::AID-CNCR1478>3.0.CO;2-H
Yukihiko Kitamura, Seiichi Hirota, Toshirou Nishida, Gastrointestinal stromal tumors (GIST): A model for molecule-based diagnosis and treatment of solid tumors Cancer Science. ,vol. 94, pp. 315- 320 ,(2003) , 10.1111/J.1349-7006.2003.TB01439.X
Guillermo A Herrera, C. Bruce Alexander, Heleno Pinto DeMoraes, Ultrastructural Subtypes of Pulmonary Adenocarcinoma Chest. ,vol. 84, pp. 581- 586 ,(1983) , 10.1378/CHEST.84.5.581
M. E. Garber, O. G. Troyanskaya, K. Schluens, S. Petersen, Z. Thaesler, M. Pacyna-Gengelbach, M. van de Rijn, G. D. Rosen, C. M. Perou, R. I. Whyte, R. B. Altman, P. O. Brown, D. Botstein, I. Petersen, Diversity of gene expression in adenocarcinoma of the lung Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 13784- 13789 ,(2001) , 10.1073/PNAS.241500798
C. Sotiriou, S.-Y. Neo, L. M. McShane, E. L. Korn, P. M. Long, A. Jazaeri, P. Martiat, S. B. Fox, A. L. Harris, E. T. Liu, Breast cancer classification and prognosis based on gene expression profiles from a population-based study Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 10393- 10398 ,(2003) , 10.1073/PNAS.1732912100
Christoph A Ritter, Carlos L Arteaga, The epidermal growth factor receptor–tyrosine kinase: A promising therapeutic target in solid tumors Seminars in Oncology. ,vol. 30, pp. 3- 11 ,(2003) , 10.1053/SONC.2003.50027