作者: David F. Ransohoff
DOI: 10.1038/NRC1550
关键词: Molecular marker 、 Psychology 、 Computational biology 、 Omics 、 Cancer 、 Interpretation (philosophy) 、 Cancer research 、 Oncology
摘要: Claims that molecular markers can accurately diagnose cancer have recently been disputed; some prominent results not reproduced and bias has proposed to explain the original observations. As new '-omics' fields are explored assess for cancer, will increasingly be recognized as most important 'threat validity' must addressed in design, conduct interpretation of such research.