The noncoding RNAs SNORD50A and SNORD50B-mediated TRIM21-GMPS interaction promotes the growth of p53 wild-type breast cancers by degrading p53.
作者： Meiju Ji , Wei Qiang , Xi Su , Peng Hou , Simeng Wang
DOI: 10.1038/S41418-021-00762-7
关键词: Biology 、 Cell cycle checkpoint 、 Wild type 、 Ubiquitin 、 Small nucleolar RNA 、 Cancer 、 Cancer cell 、 Cancer research 、 Breast cancer 、 Ubiquitin ligase
摘要: … from Gene Pharma (Shanghai, China). All fluorescence polarization … /B in MCF-7 and DU4475 cells attenuated the interaction … /B in MCF-7 and DU4475 cells, and found that ectopic …
nature.com
sci-hub.st 参考文章(55)
Adam R. Blanden, Xin Yu, Stewart N. Loh, Arnold J. Levine, Darren R. Carpizo, Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer. Drug Discovery Today. ,vol. 20, pp. 1391- 1397 ,(2015) , 10.1016/J.DRUDIS.2015.07.006
Valeria Cambiaghi, Virginia Giuliani, Sara Lombardi, Cristiano Marinelli, Francesca Toffalorio, Pier Giuseppe Pelicci, TRIM proteins in cancer. Advances in Experimental Medicine and Biology. ,vol. 770, pp. 77- 91 ,(2012) , 10.1007/978-1-4614-5398-7_6
Mária Pukáncsik, Ágnes Orbán, Kinga Nagy, Koichi Matsuo, Kunihiko Gekko, Damien Maurin, Darren Hart, István Kézsmárki, Beata G. Vertessy, Secondary Structure Prediction of Protein Constructs Using Random Incremental Truncation and Vacuum-Ultraviolet CD Spectroscopy PLOS ONE. ,vol. 11, ,(2016) , 10.1371/JOURNAL.PONE.0156238
T. Kiss, Small nucleolar RNA‐guided post‐transcriptional modification of cellular RNAs The EMBO Journal. ,vol. 20, pp. 3617- 3622 ,(2001) , 10.1093/EMBOJ/20.14.3617
Ritsuko Tanaka, Hitoshi Satoh, Masatsugu Moriyama, Kasumi Satoh, Yasuyuki Morishita, Syouko Yoshida, Toshiki Watanabe, Yoshikazu Nakamura, Shigeo Mori, Intronic U50 small‐nucleolar‐RNA (snoRNA) host gene of no protein‐coding potential is mapped at the chromosome breakpoint t(3;6)(q27;q15) of human B‐cell lymphoma Genes to Cells. ,vol. 5, pp. 277- 287 ,(2000) , 10.1046/J.1365-2443.2000.00325.X
Donna L Mallery, Leo C James, William A McEwan, Jerry C H Tam, Ruth E Watkinson, Susanna R Bidgood, Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21 Nature Immunology. ,vol. 14, pp. 327- 336 ,(2013) , 10.1038/NI.2548
Ran Brosh, Varda Rotter, When mutants gain new powers: news from the mutant p53 field Nature Reviews Cancer. ,vol. 9, pp. 701- 713 ,(2009) , 10.1038/NRC2693
Mark Wade, Yao-Cheng Li, Geoffrey M Wahl, None, MDM2, MDMX and p53 in oncogenesis and cancer therapy. Nature Reviews Cancer. ,vol. 13, pp. 83- 96 ,(2013) , 10.1038/NRC3430
Audrey Petitjean, Ewy Mathe, Shunsuke Kato, Chikashi Ishioka, Sean V. Tavtigian, Pierre Hainaut, Magali Olivier, Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Human Mutation. ,vol. 28, pp. 622- 629 ,(2007) , 10.1002/HUMU.20495
Ismail Jatoi, None, Postmastectomy radiotherapy in patients with breast cancer. The Lancet. ,vol. 384, pp. 1844- 1845 ,(2014) , 10.1016/S0140-6736(14)62237-6