Tailored medicine: Whom will it fit? The ethics of patient and disease stratification

作者: Andrew Smart , Paul Martin , Michael Parker

DOI: 10.1111/J.1467-8519.2004.00400.X

关键词: Identification (information)Drug developmentJustice (ethics)InjusticePharmacologyDiseaseAlternative medicineSocial stratificationPharmacogeneticsEngineering ethicsMedicine

摘要: A key selling point of pharmacogenetics is the genetic stratification either patients or diseases in order to target prescribing medicine. The hope that genetically ‘tailored’ medicines will replace current ‘one-size-fits-all’ paradigm drug development and usage. This paper concerned with relationship between difference justice use pharmacogenetics. This  new  technology,  which  facilitates  the  identification difference, has, we shall argue, potential lead injustice by inappropriate through failure difference. We build on empirical data from a detailed study range options for present consideration ethical issues surround patient disease stratification. In it explore ways which may creation new, stratified, forms new based these divisions. also examine existing social interact conclusion, suggest how an understanding could usefully inform future policy discussions.

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