GENETICS: Enhanced: Toward a New Vocabulary of Human Genetic Variation

作者: P. Sankar

DOI: 10.1126/SCIENCE.1074447

关键词:

摘要: This paper proposes a new framework for engaging in dialogue about the validity of race as variable genetic variation research. Rather than arguing or against race, proposing substitute such markers ethnicity, asks researchers to carefully consider what purpose they are using define and use term consistently, be aware that is not fixed biological entity, but only one way among many describe human variation.

参考文章(22)
Mark D. Shriver, Joshua M. Akey, Ranjan Deka, Robert E. Ferrell, Michael W. Smith, Amy Marcini, Li Jin, Ethnic-affiliation estimation by use of population-specific DNA markers. American Journal of Human Genetics. ,vol. 60, pp. 957- 964 ,(1997)
Paradigm lost: race, ethnicity, and the search for a new population taxonomy American Journal of Public Health. ,vol. 91, pp. 1049- 1055 ,(2001) , 10.2105/AJPH.91.7.1049
Ellen Fritsche, Gary S Pittman, Douglas A Bell, Localization, sequence analysis, and ethnic distribution of a 96-bp insertion in the promoter of the human CYP2E1 gene. Mutation Research/Mutation Research Genomics. ,vol. 432, pp. 1- 5 ,(2000) , 10.1016/S1383-5726(99)00009-6
L. B. Jorde, A. R. Rogers, M. Bamshad, W. S. Watkins, P. Krakowiak, S. Sung, J. Kere, H. C. Harpending, Microsatellite diversity and the demographic history of modern humans Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 3100- 3103 ,(1997) , 10.1073/PNAS.94.7.3100
Kelly Owens, Mary-Claire King, Genomic Views of Human History Science. ,vol. 286, pp. 451- 453 ,(1999) , 10.1126/SCIENCE.286.5439.451
Daniel W Nebert, Eula Bingham, Pharmacogenomics: out of the lab and into the community. Trends in Biotechnology. ,vol. 19, pp. 519- 523 ,(2001) , 10.1016/S0167-7799(01)01805-4
L. L. Cavalli-Sforza, Paolo Menozzi, Alberto Piazza, The history and geography of human genes ,(1994)
Chiara Romualdi, David Balding, Ivane S Nasidze, Gregory Risch, Myles Robichaux, Stephen T Sherry, Mark Stoneking, Mark A Batzer, Guido Barbujani, Patterns of Human Diversity, within and among Continents, Inferred from Biallelic DNA Polymorphisms Genome Research. ,vol. 12, pp. 602- 612 ,(2002) , 10.1101/GR.214902