Exclusion of the dysplastic nevus syndrome (DNS) locus from the short arm of chromosome 1 by linkage studies in dutch families
作者： Arie van Haeringen , Wilma Bergman , Marcel R. Nelen , Ellien van der Kooij-Meijs , Iems Hendrikse
DOI: 10.1016/0888-7543(89)90086-4
关键词: Melanoma 、 Dysplastic nevus syndrome 、 Genetics 、 Variable size 、 Genetic linkage 、 Locus (genetics) 、 Genetic marker 、 Biology 、 Chromosome 、 Gene
摘要: Familial dysplastic nevus syndrome (DNS) is an autosomal dominant premalignant condition characterized by multiple large moles of variable size and color a strongly increased risk for cutaneous malignant melanoma. In order to determine the chromosomal localization DNS gene, linkage studies were initiated in six Dutch families. No support was obtained between loci rhesus blood group on chromosome 1. Data from additional markers (DNF15S1, D1Z2, FUCA1, D1S17, D1S57, PGM1) make it possible exclude gene short arm 1 these
elsevier.com
sci-hub.se 参考文章(19)
J M Lalouel, G M Lathrop, Easy calculations of lod scores and genetic risks on small computers. American Journal of Human Genetics. ,vol. 36, pp. 460- 465 ,(1984)
P Fábry, Z Hejl, J Fodor, T Braun, Kamila Zvolánková, THE FREQUENCY OF MEALS. ITS RELATION TO OVERWEIGHT, HYPERCHOLESTEROLAEMIA, AND DECREASED GLUCOSE-TOLERANCE. The Lancet. ,vol. 2, pp. 614- 615 ,(1964) , 10.1016/S0140-6736(64)90510-0
David E. Elder, Mark H. Green, DuPont Guerry, Kenneth H. Kraemer, Wallace H. Clark, The dysplastic nevus syndrome: our definition. American Journal of Dermatopathology. ,vol. 4, pp. 455- 460 ,(1982) , 10.1097/00000372-198210000-00014
M. H. Hofker, M. C. Wapenaar, Nicole Goor, E. Bakker, G. -J. B. van Ommen, P. L. Pearson, Isolation of probes detecting restriction fragment length polymorphisms from X chromosome-specific libraries: potential use for diagnosis of Duchenne muscular dystrophy. Human Genetics. ,vol. 70, pp. 148- 156 ,(1985) , 10.1007/BF00273073
P.M. STEIJLEN, W. BERGMAN, J. HERMANS, E. SCHEFFER, W.A. VLOTEN, D.J. RUITER, The efficacy of histopathological criteria required for diagnosing dysplastic naevi Histopathology. ,vol. 12, pp. 289- 300 ,(1988) , 10.1111/J.1365-2559.1988.TB01943.X
Gert-Jan B.van Ommen, Annika C. Arnberg, Frank Baas, Huguette Brocas, Andrè Sterk, Wil H.H. Tegelaers, Gilbert Vassart, Jan J.M.de Vijlder, The human thyroglobulin gene contains two 15-17 kb introns near its 3'-end. Nucleic Acids Research. ,vol. 11, pp. 2273- 2285 ,(1983) , 10.1093/NAR/11.8.2273
Wallace H. Clark, Origin of familial malignant melanomas from heritable melanocytic lesions. 'The B-K mole syndrome'. Archives of Dermatology. ,vol. 114, pp. 732- 738 ,(1978) , 10.1001/ARCHDERM.1978.01640170032006
M. H. Greene, L. R. Goldin, W. H. Clark, E. Lovrien, K. H. Kraemer, M. A. Tucker, D. E. Elder, M. C. Fraser, S. Rowe, Familial cutaneous malignant melanoma: autosomal dominant trait possibly linked to the Rh locus Proceedings of the National Academy of Sciences of the United States of America. ,vol. 80, pp. 6071- 6075 ,(1983) , 10.1073/PNAS.80.19.6071
N.E. Morton, G.A. Bruns, Report of the committee on the genetic constitution of chromosomes 1 and 2 Cytogenetic and Genome Research. ,vol. 46, pp. 102- 130 ,(1985) , 10.1159/000132473
Robert D. Cardiff, Cellular and molecular aspects of neoplastic progression in the mammary gland. European Journal of Cancer and Clinical Oncology. ,vol. 24, pp. 15- 20 ,(1988) , 10.1016/0277-5379(88)90171-X