Peripheral neuropathy in patients with multiple sclerosis.
作者： Adnan Khan , Saadat Kamran , Georgios Ponirakis , Naveed Akhtar , Rabia Khan
DOI: 10.1371/JOURNAL.PONE.0193270
关键词: Vibration perception 、 Sudomotor 、 Sudomotor dysfunction 、 Multiple sclerosis 、 In patient 、 Peripheral neuropathy 、 Neurological disability 、 Internal medicine 、 Medicine 、 Neuropathic pain
摘要: Objectives To determine the prevalence and severity of neuropathic pain, sudomotor dysfunction abnormal vibration perception in patients with MS. Methods 73 MS 32 age-matched healthy controls underwent assessment expanded disability score (EDSS), DN4 to assess electrochemical skin conductance (ESC) function threshold (VPT). Results Patients had a higher (p < 0.001) 14% fulfilling criteria for pain elevated VPT lower ESC on feet hands compared control participants. (32% patients) (30% were lower, (77% (64% greater than 2SD values, respectively. EDSS correlated number relapses (r = 0.564, p 0.001), –0.457, –0.268, 0.023). Conclusions multiple sclerosis have evidence perception, which associated neurological from MS.
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Letizia Leocani, Giancarlo Comi, Clinical neurophysiology of multiple sclerosis Handbook of Clinical Neurology. ,vol. 122, pp. 671- 679 ,(2014) , 10.1016/B978-0-444-52001-2.00028-5
Aaron I. Vinik, Marie-Laure Nevoret, Carolina Casellini, The New Age of Sudomotor Function Testing: A Sensitive and Specific Biomarker for Diagnosis, Estimation of Severity, Monitoring Progression, and Regression in Response to Intervention. Frontiers in Endocrinology. ,vol. 6, pp. 94- 94 ,(2015) , 10.3389/FENDO.2015.00094
Arzu Guclu-Gunduz, Seyit Citaker, Bijen Nazliel, Ceyla Irkec, None, Upper extremity function and its relation with hand sensation and upper extremity strength in patients with multiple sclerosis. NeuroRehabilitation. ,vol. 30, pp. 369- 374 ,(2012) , 10.3233/NRE-2012-0768
Luka Crnošija, Ivan Adamec, Mila Lovrić, Anamari Junaković, Magdalena Krbot Skorić, Ivo Lušić, Mario Habek, Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis Clinical Neurophysiology. ,vol. 127, pp. 864- 869 ,(2016) , 10.1016/J.CLINPH.2015.06.010
JoséA. Gutrecht, Guillermo A. Suarez, Bruce E. Denny, Sympathetic skin response in multiple sclerosis. Journal of the Neurological Sciences. ,vol. 118, pp. 88- 91 ,(1993) , 10.1016/0022-510X(93)90251-S
Marcin Uszynski, Helen Purtill, Susan Coote, Relationship between foot vibration threshold and walking and balance functions in people with Multiple Sclerosis (PwMS) Gait & Posture. ,vol. 41, pp. 228- 232 ,(2015) , 10.1016/J.GAITPOST.2014.10.010
A. G. Beiske, E. D. Pedersen, B. Czujko, K.-M. Myhr, Pain and sensory complaints in multiple sclerosis. European Journal of Neurology. ,vol. 11, pp. 479- 482 ,(2004) , 10.1111/J.1468-1331.2004.00815.X
L. Grau-López, S. Sierra, E. Martínez-Cáceres, C. Ramo-Tello, Análisis del dolor en pacientes con esclerosis múltiple Neurologia. ,vol. 26, pp. 208- 213 ,(2011) , 10.1016/J.NRL.2010.07.014
A. Saari, U. Tolonen, E. Pääkkö, K. Suominen, J. Pyhtinen, K. A. Sotaniemi, J. Jauhiainen, V. V. Myllylä, Sympathetic skin responses in multiple sclerosis Acta Neurologica Scandinavica. ,vol. 118, pp. 226- 231 ,(2008) , 10.1111/J.1600-0404.2008.01003.X
Anne Saari, Uolevi Tolonen, Eija Pääkkö, Kalervo Suominen, Jukka Jauhiainen, Kyösti A. Sotaniemi, Vilho V. Myllylä, Sudomotor dysfunction in patients with optic neuritis Clinical Autonomic Research. ,vol. 20, pp. 199- 204 ,(2010) , 10.1007/S10286-009-0052-Z