Randomized clinical trial of deep lamellar keratoplasty vs penetrating keratoplasty.

摘要: Abstract PURPOSE: To prospectively compare the safety and efficacy of deep lamellar keratoplasty (DLKP) penetrating (PKP). DESIGN: Prospective, randomized clinical trial. METHODS: Consecutive 26 eyes 24 patients who had stromal opacity without endothelial abnormalities were randomly assigned to either PKP or DLKP. Best-corrected visual acuity (BCVA), contrast acuity, glare test, intraocular pressure, corneal topography, density, pachymetry measured before after surgery. RESULTS: Two in DLKP rupture Descemet membrane one developed decompensation. One eye group showed decreases vision due secondary glaucoma. None immunologic rejection. The a tendency faster recovery BCVA than group, but difference was not statistically significant. Contrast topography did show significant differences between two groups. pressure significantly higher at 12 months ( P = .004), .41) compared with preoperative values. While progressive decrease density over months, this observed Difference reached statistical significance .04). CONCLUSIONS: We found that superior its such as continuous endothelium increases pressure. However, damage can also occur DLKP, especially cases intraoperative rupture. With development easier surgical techniques, may be first choice most abnormalities.