Identification of Individuals at Risk for Lynch Syndrome Using Targeted Evaluations and Genetic Testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer Joint Practice Guideline
作者： Scott M. Weissman , Randall Burt , James Church , Steve Erdman , Heather Hampel
DOI: 10.1007/S10897-011-9465-7
关键词: Medicine 、 Genetic counseling 、 Human genetics 、 Gynecology 、 Public health 、 Family medicine 、 Lynch syndrome 、 Family history 、 Genetic testing 、 Guideline 、 Identification (information)
摘要: Identifying individuals who have Lynch syndrome (LS) involves a complex diagnostic work up that includes taking detailed family history and combination of various genetic immunohistochemical tests. The National Society Genetic Counselors (NSGC) the Collaborative Group Americas on Inherited Colorectal Cancer (CGA-ICC) come together to publish this clinical practice testing guideline for evaluation LS. purpose is provide guidance algorithm LS as well recommendations when offer testing. This does not replace consultation with genetics professional. explanations in support summary background data. While intended serve review LS, it discussion information cites number key publications which should be reviewed more in-depth understanding These guidelines are counselors, geneticists, gastroenterologists, surgeons, medical oncologists, obstetricians gynecologists, nurses other healthcare providers evaluate patients
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