Herpes simplex virus detection from genital lesions: a comparative study using antigen detection (HerpChek) and culture.

作者： R W Cone , P D Swenson , A C Hobson , M Remington , L Corey

DOI: 10.1128/JCM.31.7.1774-1776.1993

关键词: Alphaherpesvirinae 、 Herpes Genitalis 、 Simplexvirus 、 Virology 、 Herpes simplex virus 、 Herpesviridae 、 Virus 、 HSL and HSV 、 Immunoassay 、 Pathology 、 Biology

摘要: The sensitivity of a rapid enzyme immunoassay test (HerpChek Direct Herpes Simplex Virus Antigen Test [DuPont Medical Products, Wilmington, Del.]) for the detection herpes simplex virus (HSV) antigens in patient specimens was compared with HSV culture. HerpChek positivity occurred 179 (65%) 275 lesion specimens, whereas culture positive 145 (53%) lesions (P = 0.002). twice as sensitive late-stage and equivalent to early lesions. We conclude that provides greater than genital