Polypeptides having kinase activity, their preparation and use
作者： Stefano Volinia , Ian D. Hiles , George Panayotou , Michael D. Waterfield , Ritu Dhand
DOI:
关键词: Cell growth 、 Pi 、 Kinase activity 、 Biology 、 Insect cell 、 Biochemistry 、 Cell biology 、 Recombinant DNA
摘要: This invention relates to new polypeptides which exhibit kinase activity or, more specifically, show phosphoinositide (PI) 3-kinase activity. Such are involved in pathways responsible for cellular growth and differentiation. An isolated polypeptide possesses PI3-kinase when produced by recombinant production insect cells is disclosed.
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