Ganglion-cell tumor of the filum terminale: immunohistochemical characterization.

摘要: A case of an unusual spinal neuronal tumor is described in a 36-year-old woman presenting with buttock pain. The was fully characterized by neuroradiological means, and particular MRI significant value delineating the extension within canal its exophitic growth pattern. Pathologically, well circumscribed originating from intradural filum terminale characteristically comprised both large small cells, resembling mature immature respectively. In addition, two markers, i.e., chromogranin (CGA) neuron-specific enolase (NSE), other markers such as glial fibrilary acidic protein (GFAP), S-100 protein, HNK-1, tyrosine hydroxylase beta 2-microgloblin were investigated immunohistochemically. We found that cells expressed immunoreactivity for CGA NSE, showed more intense immunoreactivity, indicating earlier stage differentiation. Weakly positive HNK-1 also demonstrated consistent evidence maturation along From these findings pathological diagnosis ganglioneuroma made. This unique group ganglion-cell tumors reviewed literature differential immunohistochemical features are discussed.