Recent Developments in Pd-Catalyzed Direct Arylations of Heteroarenes with Aryl Halides
作者： Fabio Bellina
关键词: Palladium 、 Reaction conditions 、 Catalysis 、 Chemistry 、 Combinatorial chemistry 、 Reagent 、 Stoichiometry 、 Aryl 、 Halide 、 Regioselectivity
摘要: The direct arylation of heteroaromatic compounds with aryl halides using palladium catalysts has significantly been developed as an effective method for making (hetero)aryl-heteroaryl bonds, which are frequently found in biologically active and functional materials. However, issues regarding costly reagents, regioselectivity, harsh reaction conditions have to be solved really compete the classical transition metal-mediated cross-coupling procedures involving stoichiometric organometallic reagents. In this review, most relevant developments aimed at solving these summarized.
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