Somatosensory mechanisms in zebrafish lacking dorsal root ganglia

作者: Yasuko Honjo , Laurel Payne , Judith S. Eisen

DOI: 10.1111/J.1469-7580.2010.01337.X

关键词: GanglionDorsal root ganglionZebrafishNeuroscienceAnatomySomatosensory systemRegulation of gene expressionMutantNeural crestBiologySensory system

摘要: Dorsal root ganglion (DRG) sensory neurons transmit all somatosensory information from the trunk region of body. erbb3 mutant zebrafish do not form DRG because neural crest cells that generate them migrate aberrantly. Here we report homozygous mutants appear to swim and feed normally, they survive through adulthood, despite never forming neurons. The source compensation in adult remains unknown, although it may be lateral line neuromasts which are reduced, but present, mutants. We also provide new about development wild-type juvenile zebrafish.

参考文章(35)
Nicole Le Douarin, Chaya Kalcheim, The neural crest Cambridge University Press. ,(1999) , 10.1017/CBO9780511897948
David W. Raible, Gregory J. Kruse, Organization of the lateral line system in embryonic zebrafish. The Journal of Comparative Neurology. ,vol. 421, pp. 189- 198 ,(2000) , 10.1002/(SICI)1096-9861(20000529)421:2<189::AID-CNE5>3.0.CO;2-K
Paul D. Henion, David W. Raible, Christine E. Beattie, Kirsten L. Stoesser, James A. Weston, Judith S. Eisen, Screen for mutations affecting development of zebrafish neural crest Developmental Genetics. ,vol. 18, pp. 11- 17 ,(1996) , 10.1002/(SICI)1520-6408(1996)18:1<11::AID-DVG2>3.0.CO;2-4
Evdokia Menelaou, Erin E. Husbands, Robin G. Pollet, Christopher A. Coutts, Declan W. Ali, Kurt R. Svoboda, Embryonic motor activity and implications for regulating motoneuron axonal pathfinding in zebrafish. European Journal of Neuroscience. ,vol. 28, pp. 1080- 1096 ,(2008) , 10.1111/J.1460-9568.2008.06418.X
Judith S. Eisen, Rosario Reyes, Melissa Haendel, Deanna Grant, Ellie Melancon, Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death. Developmental Dynamics. ,vol. 229, pp. 30- 41 ,(2004) , 10.1002/DVDY.10488
Jason T. Rifkin, Valerie J. Todd, Lawrence W. Anderson, Frances Lefcort, Dynamic Expression of Neurotrophin Receptors during Sensory Neuron Genesis and Differentiation Developmental Biology. ,vol. 227, pp. 465- 480 ,(2000) , 10.1006/DBIO.2000.9841
David M. Parichy, Michael R. Elizondo, Margaret G. Mills, Tiffany N. Gordon, Raymond E. Engeszer, Normal table of postembryonic zebrafish development: staging by externally visible anatomy of the living fish. Developmental Dynamics. ,vol. 238, pp. 2975- 3015 ,(2009) , 10.1002/DVDY.22113
E. H. Budi, L. B. Patterson, D. M. Parichy, Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation Development. ,vol. 135, pp. 2603- 2614 ,(2008) , 10.1242/DEV.019299