Fermentative lifestyle in yeasts belonging to the Saccharomyces complex

摘要: The yeast Saccharomyces cerevisiae is characterized by its ability to: (a) degrade glucose or fructose to ethanol, even in the presence of oxygen (Crabtree effect); (b) grow absence oxygen; and (c) generate respiratory-deficient mitochondrial mutants, so-called petites. How unique are these properties among yeasts clade, what their origin? Recent progress genome sequencing has elucidated phylogenetic relationships complex, providing a framework for understanding evolutionary history several modern traits. In this study, we analyzed over 40 that reflect 150 million years ferment, oxygen, A great majority isolates exhibited good fermentation ability, suggesting trait could already be an intrinsic property progenitor yeast. We found lineages underwent whole-genome duplication, general, exhibit fermentative lifestyle, Crabtree effect, without can stable petite mutants. Some pre-genome duplication also some traits, but tested species petite-negative, show reduced effect oxygen. It accumulate ethanol gradual independence from and/or petites were developed later lineages. However, traits have been combined perfection only lineage led