Inhibitors Around the Antimycin-Sensitive Site in the Respiratory Chain

摘要: The region of the respiratory chain between cytochromes b and c1 is affected by several compounds in such a way as to lead inhibition electron transport. site action these inhibitors usually called “antimycin-sensitive” because antimycin [1] most firmly bound. Three main classes will be considered here: (i) antimycin, (ii) alkyl derivatives 4-hydroxyquinoline-N-oxide (iii) 3-hydroxy-1,4-naphthoquinone. Their application studies on structure function has been manyfold: (a) elucidation sequence components [58], (b) reconstitution [39], (c) oxidative phosphorylation [59] especially estimating sites (d) reversal [33, 41].