A retrospective study on malignant neoplasms of bladder, lung and liver in blackfoot disease endemic area in Taiwan.
作者： C J Chen , Y C Chuang , S L You , T M Lin , H Y Wu
DOI: 10.1038/BJC.1986.65
关键词: Odds ratio 、 Pathology 、 Medicine 、 Hepatobiliary disease 、 Liver cancer 、 Urinary bladder 、 Retrospective cohort study 、 Internal medicine 、 Lung cancer 、 Bladder cancer 、 Epidemiology
摘要: A total of 69 bladder cancer, 76 lung cancer and 59 liver deceased cases 368 alive community controls group-matched on age sex were studied to evaluate the association between high-arsenic artesian well water cancers in endemic area blackfoot disease (BFD), a unique peripheral vascular related continuous arsenic exposure. According standardized structured questionnaire, information risk factors was obtained through proxy interview personal controls. positive dose-response relationship observed exposure bladder, liver. The age-sex-adjusted odds ratios developing for those who had used 40 or more years 3.90, 3.39, 2.67, respectively, as compared with never water. Multiple binary logistic regression analyses showed that relationships remained much same while other further adjusted.
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