作者: S. C. USHINSKY , H. BUSSEY , A. A. AHMED , Y. WANG , J. FRIESEN
DOI: 10.1002/(SICI)1097-0061(199702)13:2<151::AID-YEA94>3.0.CO;2-5
关键词: HDAC11 、 Histone H2A 、 SAP30 、 Histone methylation 、 HDAC10 、 Biology 、 Histone methyltransferase 、 Molecular biology 、 Heterochromatin protein 1 、 Histone H1
摘要: The existence of histone H1 in the yeast, Saccharomyces cerevisiae, has long been debated. In this report we describe presence yeast. YPL127c, a gene encoding protein with high degree similarity to from other species was sequenced as part contribution Montreal Yeast Genome Sequencing Group chromosome XVI. To reflect similarity, designation changed HHO1 (Histone H One). is highly expressed poly A+ RNA Although deletion had no detectable effect on cell growth, viability or mating, it significantly altered expression β-galactosidase CYC1-lacZ reporter. Fluorescence observed cells expressing H1-GFP fusion indicated that localized nucleus.©1997 John Wiley & Sons, Ltd.