Antigenic and Genetic Diversity of Human Enterovirus 71 from 2009 to 2012, Taiwan
作者： Yuan-Pin Huang , Tsuey-Li Lin , Ting-Han Lin , Ho-Sheng Wu
DOI: 10.1371/JOURNAL.PONE.0080942
关键词: Neutralization 、 Antigenic Diversity 、 Genetic variation 、 Virology 、 Outbreak 、 Phylogenetic tree 、 Biology 、 Genetics 、 Genetic diversity 、 Phylogenetics 、 Enterovirus 71 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: Different subgenogroups of enterovirus 71 (EV-71) have caused numerous outbreaks hand, foot, and mouth disease worldwide, especially in the Asia-Pacific region. During development a vaccine against EV-71, genetic antigenic diversities EV-71 isolates from Taiwan were analyzed by phylogenetic analyses neutralization tests. The results showed that dominant genogroups had changed twice, B to C B, between 2009 2012. subgenogroup B5 (B5b cluster) was 2008-2009 but replaced C4 2010-2011. From end 2011 2012, re-emerging (B5c identified as outbreaks, C2 detected sporadic cases. Interestingly, amino acid substitution at position 145 VP1 gene observed some strains isolated patients with acute flaccid paralysis. Furthermore, thirty-five their corresponding serum samples used analyze cross-protections among different (C4a, C5, B4, B5b, B5c, C2-like) EV-71. Evident diversity existed only for C2-like subgenogroup, which not effectively neutralized other samples. In contrast, anti-C2-like sample broad cross-reactivity all subgenogroups. Therefore, these may provide valuable information selection candidates evolution
cdc.gov
paperity.org
core.ac.uk 参考文章(40)
P. P. Francis, J. M. Deshpande, S. S. Nadkarni, Enterovirus 71 isolated from a case of acute flaccid paralysis in India represents a new genotype Current Science. ,vol. 84, pp. 1350- 135325 ,(2003)
Chan Yoke-Fun, Sazaly AbuBakar, Phylogenetic evidence for inter-typic recombination in the emergence of human enterovirus 71 subgenotypes BMC Microbiology. ,vol. 6, pp. 74- 74 ,(2006) , 10.1186/1471-2180-6-74
T. Munemura, M. Saikusa, C. Kawakami, H. Shimizu, M. Oseto, A. Hagiwara, H. Kimura, T. Miyamura, Genetic diversity of enterovirus 71 isolated from cases of hand, foot and mouth disease in Yokohama City between 1982 and 2000. Archives of Virology. ,vol. 148, pp. 253- 263 ,(2003) , 10.1007/S00705-002-0920-5
Abby Seiff, Cambodia unravels cause of mystery illness The Lancet. ,vol. 380, pp. 205- ,(2012) , 10.1016/S0140-6736(12)61200-8
Kuei-Hsiang Lin, Kao-Pin Hwang, Guan-Ming Ke, Chu-Feng Wang, Liang-Yin Ke, Yu-Ting Hsu, Yi-Chin Tung, Pei-Yu Chu, Bai-Hsiun Chen, Hsiu-Lin Chen, Chuan-Liang Kao, Jen-Ren Wang, Hock-Liew Eng, Sheng-Yu Wang, Li-Ching Hsu, Hour-Young Chen, Evolution of EV71 genogroup in Taiwan from 1998 to 2005: an emerging of subgenogroup C4 of EV71. Journal of Medical Virology. ,vol. 78, pp. 254- 262 ,(2006) , 10.1002/JMV.20534
Damian Guang Wei Foo, Paul A. Macary, Sylvie Alonso, Chit Laa Poh, Identification of human CD4 T-cell epitopes on the VP1 capsid protein of enterovirus 71. Viral Immunology. ,vol. 21, pp. 215- 224 ,(2008) , 10.1089/VIM.2007.0089
Damian Guang Wei Foo, Sylvie Alonso, Meng Chee Phoon, N.P. Ramachandran, Vincent Tak Kwong Chow, Chit Laa Poh, Identification of Neutralizing Linear Epitopes From the VP1 Capsid Protein of Enterovirus 71 Using Synthetic Peptides Virus Research. ,vol. 125, pp. 61- 68 ,(2007) , 10.1016/J.VIRUSRES.2006.12.005
Yuan-Pin Huang, Tsuey-Li Lin, Chuan-Yi Kuo, Miao-Wen Lin, Ching-Yuan Yao, Hui-Wen Liao, Li-Ching Hsu, Chen-Fu Yang, Jyh-Yuan Yang, Pei-Jer Chen, Ho-Sheng Wu, The circulation of subgenogroups B5 and C5 of enterovirus 71 in Taiwan from 2006 to 2007. Virus Research. ,vol. 137, pp. 206- 212 ,(2008) , 10.1016/J.VIRUSRES.2008.07.015
Phan Van Tu, Nguyen Thi Thanh Thao, David Perera, Khanh Huu Truong, Nguyen Thi Kim Tien, Tang Chi Thuong, Ooi Mong How, Mary Jane Cardosa, Peter Charles McMinn, Epidemiologic and virologic investigation of hand, foot, and mouth disease, southern Vietnam, 2005. Emerging Infectious Diseases. ,vol. 13, pp. 1733- 1741 ,(2007) , 10.3201/EID1311.070632
K. Mizuta, Y. Aoki, A. Suto, K. Ootani, N. Katsushima, T. Itagaki, A. Ohmi, M. Okamoto, H. Nishimura, Y. Matsuzaki, S. Hongo, K. Sugawara, H. Shimizu, T. Ahiko, Cross-antigenicity among EV71 strains from different genogroups isolated in Yamagata, Japan, between 1990 and 2007 Vaccine. ,vol. 27, pp. 3153- 3158 ,(2009) , 10.1016/J.VACCINE.2009.03.060