Human immunodeficiency virus-related Epstein-Barr virus-associated smooth muscle tumours: South African experience from Chris Hani Baragwanath Academic Hospital
作者： Sugeshnee Pather , Rosalind D. Wainwright , Faieza Sahid , Thembi Mashele , Eunice J. van den Berg
DOI: 10.1080/23120053.2017.1332918
关键词: Pathology 、 Smooth muscle 、 Time frame 、 In situ hybridisation 、 Hiv seropositive 、 Paediatric patients 、 Immunohistochemistry 、 Epstein–Barr virus 、 Internal medicine 、 Medicine 、 Human immunodeficiency virus (HIV)
摘要: AbstractBackground: Despite the rampant human immunodeficiency (HIV) epidemic in Africa, there is a paucity of published data HIV-related Epstein-Barr virus-associated smooth muscle tumours (EBV-SMT) from Africa.Methods: We embarked on retrospective documentation clinicopathological features confirmed EBV-SMT over 5-year time frame at largest hospital Africa. All haematoxylin and eosin stained tissue sections, immunohistochemistry EBV situ hybridisation (ISH) investigations were reviewed conjunction with clinical data.Results: Fourteen (n = 14) 13 patients (age range: 10–53 years). Five paediatric predominance females (70%) evident this series. HIV seropositive CD4 counts ranged 1 to 1331 cells/ul (median 355 cells/ul; mean 442 cells/ul). Tumour-associated pain was common symptom age group, while neurological symptoms frequent adults due paraspinal c...
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