Meningococcal protein antigens and vaccines
作者： Ian M Feavers , Mariagrazia Pizza , None
DOI: 10.1016/J.VACCINE.2009.05.001
关键词: Vaccination 、 Antigen 、 Biology 、 Bacterial protein 、 Neisseria meningitidis 、 Disease prevention 、 Molecular genetics 、 Virology 、 Immunization 、 Meningococcal disease 、 Immunology 、 Public Health, Environmental and Occupational Health 、 General Immunology and Microbiology 、 Molecular medicine 、 General Veterinary 、 Infectious Diseases
摘要: The development of a comprehensive vaccine against meningococcal disease has been challenging. Recent developments in molecular genetics have provided both explanations for these challenges and possible solutions. Since genome sequence data became available there marked increase number protein antigens that suggested as prospective components. This review catalogues the proposed candidates examines evidence their inclusion potential formulations.
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