One‐Pot Wittig Reactions in Aqueous Media: A Rapid and Environmentally Benign Synthesis of α,β‐Unsaturated Carboxylic Esters and Nitriles
作者： Jinlong Wu , Congyong Yue
DOI: 10.1080/00397910600773684
关键词: One pot reaction 、 Ethyl bromoacetate 、 Aqueous medium 、 Aqueous reaction 、 Wittig reaction 、 Chemistry 、 Bromoacetonitrile 、 Organic chemistry 、 Olefin fiber
摘要: Abstract One‐pot Wittig reactions of ethyl bromoacetate and bromoacetonitrile with aldehydes in the presence PPh3 LiOH water were investigated. Most olefination completed within 5–120 min refluxing containing 1.2 M LiCl to afford olefin products 71–97% yields 100:0–55:45 ratios E:Z isomers.
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