Normal thoracic and abdominal distribution of 2-deoxy-2-[18F]fluoro-D-glucose (18FDG) in adult cats.
作者： BJOERN JAKOBY , DAVID W. TOWNSEND , GREGORY B. DANIEL , AMY K. LEBLANC , JON S. WALL
DOI: 10.1111/J.1740-8261.2009.01562.X
关键词: Medicine 、 Nuclear medicine 、 Spleen 、 Future studies 、 Baseline data 、 2 deoxy 2 18f fluoro d glucose 、 Pathology 、 CATS 、 Scatter correction 、 Positron emission tomography 、 Distribution (pharmacology)
摘要: Positron emission tomography (PET) with 2-deoxy-2-[18sF]fluoro-D-glucose (18FDG) is an important imaging modality for diagnosis and staging of human neoplastic disease. The purpose this study to describe the normal 18FDG uptake in adult cats. Six healthy female cats were used. Cats sedated then injected intravenously 74.0 +/- 13.0 (mean SD) MBq 18FDG. General anesthesia was induced placed ventral recumbancy on PET scanner's bed. Static images using multiple bed positions acquired approximately 60-90 min after injection. A transmission scan at each position utilizing a 57Co point source perform attenuation scatter correction. Regions interest (ROIs) drawn over liver, right left renal cortices, ventricular wall, wall ascending descending colonic segments. Standardized values (SUV) calculated established formula. Kidneys intestinal tract had relatively intense 18FDG; liver activity intermediate; spleen not identified any Cardiac variable but noted myocardium most No appreciable lung noted. Mean SD SUV calculated. This pattern provided baseline data comparison future studies evaluating variety nonneoplastic diseases.
cabdirect.org
sci-hub.se 参考文章(21)
Celso D. Ramos, Yusuf E. Erdi, Mithat Gonen, Elyn Riedel, Henry W. D. Yeung, Homer A. Macapinlac, Roland Chisin, Steven M. Larson, FDG-PET standardized uptake values in normal anatomical structures using iterative reconstruction segmented attenuation correction and filtered back-projection. web science. ,vol. 28, pp. 155- 164 ,(2001) , 10.1007/S002590000421
David W. Townsend, Mario Ca ~nadas, Cristina Lois, Bjoern W. Jakoby, Karl Hubner, Physical and Clinical Evaluation of Standardized Uptake Values Bulletin of the American Physical Society. ,(2008)
John W. Keyes, SUV: Standard Uptake or Silly Useless Value? The Journal of Nuclear Medicine. ,vol. 36, pp. 1836- 1839 ,(1995)
Rakesh Kumar, Murali R Nadig, Anil Chauhan, Positron emission tomography: clinical applications in oncology. Part 1. Expert Review of Anticancer Therapy. ,vol. 5, pp. 1079- 1093 ,(2005) , 10.1586/14737140.5.6.1079
Joanna S. Fowler, Tatsuo Ido, Initial and subsequent approach for the synthesis of 18FDG Seminars in Nuclear Medicine. ,vol. 32, pp. 6- 12 ,(2002) , 10.1053/SNUC.2002.29270
G. Lucignani, G. Paganelli, E. Bombardieri, The use of standardized uptake values for assessing FDG uptake with PET in oncology: a clinical perspective. Nuclear Medicine Communications. ,vol. 25, pp. 651- 656 ,(2004) , 10.1097/01.MNM.0000134329.30912.49
Marinke Westerterp, Jan Pruim, Wim Oyen, Otto Hoekstra, Anne Paans, Eric Visser, Jan Van Lanschot, Gerrit Sloof, Ronald Boellaard, None, Quantification of FDG PET studies using standardised uptake values in multi-centre trials: effects of image reconstruction, resolution and ROI definition parameters European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 34, pp. 392- 404 ,(2007) , 10.1007/S00259-006-0224-1
JAMES G. MORRIS, QUINTON R. ROGERS, Metabolic basis for some of the nutritional peculiarities of the cat Journal of Small Animal Practice. ,vol. 23, pp. 599- 613 ,(1982) , 10.1111/J.1748-5827.1982.TB02520.X
T Arai, T Washizu, M Sagara, T Sako, H Nigi, H Matsumoto, M Sasaki, I Tomoda, D-glucose transport and glycolytic enzyme activities in erythrocytes of dogs, pigs, cats, horses, cattle and sheep. Research in Veterinary Science. ,vol. 58, pp. 195- 196 ,(1995) , 10.1016/0034-5288(95)90078-0
F.J. Ballard, Glucose utilization in mammalian liver Comparative Biochemistry and Physiology. ,vol. 14, pp. 437- 443 ,(1965) , 10.1016/0010-406X(65)90218-5