Comparative Oncology: Evaluation of 2-Deoxy-2-[18F]fluoro-D-glucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) for the Staging of Dogs with Malignant Tumors.

摘要: Introduction 2-Deoxy-2-[18F]fluoro-D-glucose PET/CT is a well-established imaging method for staging, restaging and therapy-control in human medicine. In veterinary medicine, this could prove to be an attractive innovative alternative conventional order improve staging restaging. The aim of study was both evaluate the effectiveness image-guided canine patients with spontaneously occurring cancer as well illustrate dog well-suited animal model comparative oncology. Methods Ten dogs various malignant tumors were included underwent whole body FDG PET/CT. One patient has second PET-CT 5 months after first study. Patients diagnosed histiocytic sarcoma (n = 1),malignant lymphoma 2),mammary carcinoma 4),sertoli cell tumor 1),gastrointestinal stromal (GIST) 1) lung 1). data analyzed help 5-point scale consideration patients' medical histories. Results seven ten dogs, treatment protocol prognosis significantly changed due results 2) extent defined on because increased uptake multiple lymph nodes. This led recommendation therapeutic polychemotherapy treatment. one mammary 4) 1),surgery cancelled discovery metastasis. Consequently no recommended. Conclusion offers additional information disease potential improvement encouraging clinical highlights possibility further diagnostic methods regard future, performing not only but also therapy control offer significant management tumors.